منابع مشابه
Mathematical model for bone mineralization
Defective bone mineralization has serious clinical manifestations, including deformities and fractures, but the regulation of this extracellular process is not fully understood. We have developed a mathematical model consisting of ordinary differential equations that describe collagen maturation, production and degradation of inhibitors, and mineral nucleation and growth. We examined the roles ...
متن کاملMathematical model for the mineralization of bone.
A mathematical model is presented for the transport and precipitation of mineral in refilling osteons. One goal of this model was to explain calcification "halos," in which the bone near the haversian canal is more highly mineralized than the more peripheral lamellae, which have been mineralizing longer. It was assumed that the precipitation rate of mineral is proportional to the difference bet...
متن کاملBone mineralization.
This review attempts to summarize the findings made available by the literature on the mineralization of bone. The types of bone, their structures and compositions, the nature and organization of organic and inorganic matter, the organic-inorganic relationships, and the mineralization mechanism itself, are the main topics of the present review. As in other hard tissues, bone mineralization occu...
متن کاملMineralization of hydrogels for bone regeneration.
Hydrogels are an important class of highly hydrated polymers that are widely investigated for potential use in soft tissue engineering. Generally, however, hydrogels lack the ability to mineralize, preventing the formation of chemical bonds with hard tissues such as bone. A recent trend in tissue engineering involves the development of hydrogels that possess the capacity to mineralize. The stra...
متن کاملA Mathematical Model for Flood Protection
Many regions in the world are protected against flooding by a dike, which may be either natural or artificial. We deal with a model for finding the optimal heights of such a dike in the future. It minimizes the sum of the investments costs for upgrading the dike in the future and the expected costs due to flooding. The model is highly nonlinear, nonconvex, and infinite-dimensional. Despite this...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2015
ISSN: 2296-634X
DOI: 10.3389/fcell.2015.00051